Multi-Strategy Investment Firm

Backing visionaries and builders at the technological frontier

Big Brain Holdings is a global multi-stage investment firm backing funds and founders accelerating emerging frontiers in technology. Rooted in cypherpunk, we back conviction and visionaries pursuing radical ideas.

120+
Portfolio Companies
60+
Funds Invested
8+
Years Active
40+
Countries
Investment Thesis

We back conviction and radical ideas.

Rooted in first-principles thinking, Big Brain Holdings partners with founders who are redefining what's possible at the intersection of intelligence, autonomy, and infrastructure.

We take concentrated, long-term positions in companies with the potential to reshape industries — from AI inference and humanoid robotics to decentralized compute and consumer technology.

Artificial Intelligence

Foundation models, inference infrastructure, AI-native applications, and agentic systems.

Robotics

Humanoid robots, autonomous systems, industrial automation, and embodied AI platforms.

Decentralized Infra

Next-generation blockchain protocols, decentralized compute networks, and Web3 primitives.

Consumer & Deeptech

Consumer applications at scale and deep-technology companies solving fundamental problems.

Investments

Our Portfolio

Advanced Compute Ahead Computing High-performance RISC-V CPU Crypto Solana High-performance blockchain Deeptech Vulcan Elements Rare earth magnets Crypto Mysten Labs High-performance blockchain Crypto NEAR Protocol Open agentic infrastructure Deeptech Mach Industries Autonomous drones Consumer Pump.fun Token launchpad Crypto Sphere Global payments infrastructure Data/ AI Infra Grass Decentralized data network Data/ AI Infra Hyperbolic AI inference infrastructure AI FortyTwo Self-evolving AI network Robotics Dyna Robotics General-purpose robotics Robotics Apptronik Humanoid robotics Robotics Personal AI Industrial humanoid robotics Robotics Agility Robotics Industrial humanoid robotics Crypto Flashbots MEV infrastructure Data/ AI Infra Yotta Labs AI inference infrastructure AI Antigma Self-contained agents Robotics Daxo Robotics Dexterous hand robotics Consumer Enhanced Games Consumer health and sports event Consumer Kash Social-native prediction market Crypto Magna Digital asset management platform Crypto Monad High-performance blockchain Deeptech Teralink High bandwidth comms for space Advanced Compute Tsavorite AI accelerator Crypto Avalanche Enterprise blockchain infrastructure Crypto MegaETH Ultra-high throughput EVM Crypto Utexo Stablecoin infrastructure Crypto Arweave Permanent decentralized storage Consumer Pudgy Penguins Consumer IP Crypto Wormhole Cross-chain messaging Crypto The Graph Blockchain data indexing Crypto Stacks Bitcoin DeFi layer Crypto Solayer High-performance SVM Crypto Initia Blockchain rollup infrastructure Crypto Helius Blockchain tooling AI Ambient Inference network Crypto Bulk Perpetuals DEX Data/ AI Infra Exo Labs Distributed AI compute Robotics Bitrobot Open robotics lab Robotics Nirvana AI Industrial robotics lab Consumer Tensor On-chain trading app Crypto IKA Decentralized MPC network AI Wayfinder On-chain agentic infrastructure Consumer Parallel Life Trading card game Data/ AI Infra Perle AI AI data infrastructure AI Ritual Agentic infrastructure Data/ AI Infra Aethir AI inference infrastructure Crypto Crossmint Stablecoin infrastructure Crypto Argument Cryptographically verifiable computing Data/ AI Infra Inference Labs AI inference infrastructure Consumer Legend Onchain trading app Crypto Nubit Bitcoin data availability layer Consumer ZarPay Payments infrastructure Consumer Collector Crypt TCG app Consumer Youmio Embodied agents Crypto Bio Protocol Decentralized biotech Consumer Collective Memory Decentralized memory network Data/ AI Infra FrodoBots Crowdsourcing data network Consumer GTE Perpetuals DEX Crypto Raiku Solana infrastructure Consumer Sphinx Commodities perpetuals Crypto Reflect Yield-bearing stablecoin Crypto Arch Network Bitcoin infrastructure Data/ AI Infra Wynd AI data infrastructure Data/ AI Infra Exabits Distributed GPU compute Crypto Nillion Encryption protocol Crypto Inco On-chain privacy solutions Data/ AI Infra Akave Decentralized cloud storage Crypto Octra Decentralized FHE Crypto Hemi High-performance blockchain Data/ AI Infra USD AI AI financing Consumer Sweatcoin Health app Consumer LEVR Sports prediction market Crypto Panoptic Decentralized options protocol Crypto AVNU Starknet DeFi
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Get in Touch

Let's build something great.

If you’re a founder building next-generation technologies or a partner looking to collaborate, we’d love to hear from you.

Inquiries hello@bigbrain.holdings